What is the structure of acridine?

C13H9N
Acridine/Formula

What is acridine used for?

Acridine Orange is a cell-permeant nucleic acid binding dye that emits green fluorescence when bound to dsDNA and red fluorescence when bound to ssDNA or RNA. This unique characteristic makes acridine orange useful for cell-cycle studies. Acridine orange has also been used as a lysosomal dye.

Which one is the example of acridine derivative?

Dye molecules such as methylene blue (an acridine derivative) are known to interact with oligonucleotides by intercalation into the nucleic acids.

What is the significance of acridines in molecular biology?

Acridine derivatives have been shown to be effective as inhibitors of acetylcholinesterase. Furthermore, acridines are used as dyes, fluorescent materials for visualization of biomolecules, and in laser technologies.

What’s the definition of acridine?

: a colorless crystalline compound C13H9N occurring in coal tar and important as the parent compound of dyes and pharmaceuticals.

Which hetero atom is present in acridine?

nitrogen heterocycle
Acridine is an organic compound and a nitrogen heterocycle with the formula C13H9N. Acridines are substituted derivatives of the parent ring. It is a planar molecule that is structurally related to anthracene with one of the central CH groups replaced by nitrogen.

What is the principle of acridine orange stain?

Acridine orange is a fluorochromatic dye which binds to nucleic acids of bacteria and other cells that causes deoxyribonucleic acid (DNA) to fluoresce green and ribonucleic acid (RNA) or single stranded DNA to fluoresce orange-red under UV light.

What type of mutagen is acridine?

Simple acridines show activity as frameshift mutagens, especially in bacteriophage and bacterial assays, by virtue of their intercalative DNA-binding ability.

What are acridine dyes?

: any of a small class of basic dyes containing the acridine nucleus, most of them being yellow, orange, red, or brown, that are fluorescent in solution and are used chiefly for dyeing leather and mordanted cotton.

What is the acridine nucleus?

Acridine is a heterocyclic nucleus. It plays an important role in various medicines. A number of therapeutic agents are based on acridine nucleus such as quinacrine (antimalarial), acriflavine and proflavine (antiseptics), ethacridine (abortifacient), amsacrine and nitracine (anticancer), and tacrine.

Is acridine a mutagen?

For example, acridine dyes are mutagenic. An important finding was that while acridine-induced mutations revert spontaneously or by exposure to acridines, they are not reverted by mutagens known to induce base substitution mutations.

How is an acridine related to an anthracene molecule?

Acridine is an organic compound and a nitrogen heterocycle with the formula C13H9N. Acridines are substituted derivatives of the parent ring. It is a planar molecule that is structurally related to anthracene with one of the central CH groups replaced by nitrogen.

How are resonance structures used to describe bonding?

In many cases, a single Lewis structure fails to explain the bonding in a molecule/polyatomic ion due to the presence of partial charges and fractional bonds in it. In such cases, resonance structures are used to describe chemical bonding.

What is the molecular formula for acridine orange?

Acridine orange PubChem CID 62344 Structure Find Similar Structures Molecular Formula C17H19N3 Synonyms Acridine orange 494-38-2 Acridine Orange Molecular Weight 265.35

How many rings are there in an acridine?

Acridines are a class of heterocyclic compounds characterized by three fused six-membered rings, with a planar aromatic surface. Valentina Pirota,