What does Motofen do to your body?

This medication is used to treat diarrhea. It helps to decrease the number and frequency of bowel movements. It works by slowing the movement of the intestines. Difenoxin is similar to opioid pain relievers, but it acts mainly to slow the gut.

Is Motofen a control?

Motofen® tablets are a Schedule IV controlled substance. Addiction to (dependence on) difenoxin hydrochloride is theoretically possible at high dosage. Therefore, the recommended dosage should not be exceeded.

What is Motofen?

Each five-sided dye free MOTOFEN® tablet contains: 1 mg of difenoxin (equivalent to 1.09 mg of difenoxin hydrochloride) and 0.025 mg of atropine sulfate (equivalent to 0.01 mg of atropine). Atropine sulfate is present to discourage deliberate overdose.

What type of drug is Motofen?

Motofen (difenoxin hydrochloride and atropine sulfate) is an anticholinergic used to treat diarrhea.

Is Motofen legal?

There is currently no therapeutically equivalent version of Motofen available in the United States. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Motofen. These medications may be counterfeit and potentially unsafe.

Who makes Motofen?

There is currently only one manufacturer of Motofen tablets: Valeant Pharmaceuticals. It acquired the drug from Amarin Pharmaceuticals in 2004. Valeant’s tablets are pentagonal shaped, impressed with a “V” on one side, and vertically scored on the other side.

How does atropine help with diarrhea?

This medication is used to treat diarrhea. It helps to decrease the number and frequency of bowel movements. It works by slowing the movement of the intestines. Diphenoxylate is similar to opioid pain relievers, but it acts mainly to slow the gut.

How does atropine affect the GI tract?

Cholinergic antagonism with atropine reduces proximal gastric emptying, reduces antral contractility and notably slows gastric emptying.

Is it safe to take Motofen for diarrhea?

Motofen ® is contraindicated in patients with diarrhea associated with organisms that penetrate the intestinal mucosa (toxigenic E. coli, Salmonella species, Shigella) and pseudomembranous colitis associated with broad spectrum antibiotics.

What are the side effects of difenoxin and Motofen?

Difenoxin is metabolized to an inactive hydroxylated metabolite. Both the drug and its metabolites are excreted, mainly as conjugates, in urine and feces. Motofen® is indicated as adjunctive therapy in the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.

How often should you take Motofen for loose stool?

Motofen Dosage and Administration. The recommended starting dose of Motofen® tablets in adults is 2 tablets then 1 tablet after each loose stool or 1 tablet every 3 to 4 hours as needed, but the total dosage during any 24-hour treatment period should not exceed 8 tablets.

Do you have diarrhea with irritable bowel syndrome?

IBS that causes increased diarrhea is often called IBS-D. If you have IBS-D, you have belly pain and other IBS symptoms plus frequent bowel movements. Your stool might be loose, though not always.