How many cases of precocious puberty are there?

Precocious puberty is generally defined as the appearance of secondary sex characteristics before age 8 years in girls (or menarche before age 9 years) and before 9 years in boys. The overall incidence of sexual precocity is estimated to be 1:5,000 to 1:10,000 children. The female-to-male ratio is approximately 10:1.

What is a major consequence of precocious puberty?

Possible complications of precocious puberty include: Short height. Children with precocious puberty may grow quickly at first and be tall, compared with their peers. But, because their bones mature more quickly than normal, they often stop growing earlier than usual.

Can precocious puberty be inherited?

Interestingly, precocious puberty was inherited maternally in 21 families and paternally in 10 families. In only 4 families, precocious puberty was inherited both maternally and paternally.

What happens if you don’t treat CPP?

Without treatment, CPP can have lasting complications. If CPP is left untreated, your child can continue to experience puberty as a result, and that can have lasting complications beyond childhood. That’s why it’s important to see your child’s pediatrician if you think your child is showing signs of puberty too soon.

Is precocious puberty autosomal dominant?

The familial pattern of central precocious puberty in girls noted in the present study suggests an autosomal dominant inheritance. The possibility that precocious puberty might be familial was raised in the past.

Is precocious puberty constitutional?

The other subdivision of true precocious puberty is composed of those cases for which no obvious cause can be found and are thought to result simply from an early initiation of normal pituitary hormonal changes of puberty. These are usually re- ferned to as instances of constitutional or idiopathic precocious puberty.

Does early menarche affect fertility?

Short cycles, early or late onset of menstruation, associated with reduced fertility. Short menstrual cycle lengths and early or late onset of menstruation are associated with reduced fertility, according to a new study led by Boston University School of Public Health (SPH) researchers.

How old do you have to be to have precocious puberty?

Precocious Puberty. Usually, this starts to happen in adolescence — no earlier than about 7 to 8 years of age in girls (the average age is about 10) and 9 years of age for boys (the average age is about 11).

Are there any FDA approved treatments for precocious puberty?

FDA-approved indication: Treatment of children with central precocious puberty. FDA-approved indication: Treatment of central precocious puberty. FDA-approved indication: Treatment of central precocious puberty (gonadotropin-dependent precocious puberty) in children of both sexes.

When does precocious puberty occur in white girls?

This disorder is classically characterized among females by breast development beginning before the age of eight years in white girls, 6.8 years for Hispanic girls and 6.6 years for Black girls, or the onset of menstruation before the age of approximately ten years (white-10.6 years, Hispanic-10.0 years and black-9.7 years).

When does familial male limited precocious puberty ( FMPP ) occur?

Familial male-limited precocious puberty (FMPP), also referred to a familial testotoxicosis, is a rare genetic disorder caused by persistent activation of the LH receptor. As its name suggests, the disorder only affects males, usually presenting by 4 years of age with signs of early pubertal development.