What are functional domains of proteins?

Domains are distinct functional and/or structural units in a protein. Usually they are responsible for a particular function or interaction, contributing to the overall role of a protein.

What is a domain containing protein?

A protein domain is a region of the protein’s polypeptide chain that is self-stabilizing and that folds independently from the rest. Each domain forms a compact folded three-dimensional structure. Domains often form functional units, such as the calcium-binding EF hand domain of calmodulin.

What is structural domain?

A structural domain is an areally distinct region or subregion with similar structural properties (e.g., similar fold vergence or style, shortening, uplift, faulting style, etc.).

How many protein domains are there?

These proteins contain 808 886 protein domains, of which 190 760 were regions and 616 126 were protein sites. Protein regions are longer elements within coding genes (mean length 315.6 bp).

What is domain structure?

A domain name is an identification string that defines a realm of administrative autonomy, authority or control within the Internet. In the Domain Name structure computer IP address mappings (equivalent to files) are placed in domains, and these domains can contain other domains (sub domains).

What is the Apoptosome complex constructed from?

The apoptosome is a multimolecular holoenzyme complex assembled around the adaptor protein Apaf1 (apoptotic protease activating factor 1) upon mitochondria-mediated apoptosis which must be stimulated by some type of stress signal.

What is card immunology?

Caspase recruitment domains, or caspase activation and recruitment domains (CARDs), are interaction motifs found in a wide array of proteins, typically those involved in processes relating to inflammation and apoptosis.

How do you find the domain of a protein structure?

One way to identify a domain is to find the part of a target protein that has sequence or structural similarities with a template through homology alignment. Another way is to predict the domain boundaries from a protein sequence.

What is the domain structure?

What are the examples of domain?

Hierarchy of Domain Names