What does Treponema Denticola do?

Treponema Denticola is a potential etiological bacterial agent for oral cancer. It encourages oncogenesis (process in which healthy cells become cancer cells) and therefore the progression of oral cancer through chronic inflammation advancing invasiveness of the cancer cells.

Is Treponema Denticola anaerobic?

Treponema denticola, a periodontal pathogen, has recently been shown to exhibit properties of a facultative anaerobic spirochete, in contrast to its previous recognition as an obligate anaerobic bacterium.

What is the difference between Treponemal and Nontreponemal test?

Treponemal tests detect antibody to T pallidum proteins. Nontreponemal tests detect antibodies directed against lipoidal antigens, damaged host cells, and possibly from treponemes. Both tests are used to confirm the infection and determine whether the disease is active.

What is positive RPR test?

A positive test result may mean that you have syphilis. If the screening test is positive, the next step is to confirm the diagnosis with a more specific test for syphilis, such as FTA-ABS. The FTA-ABS test will help distinguish between syphilis and other infections or conditions.

Which bacteria is in red complex?

The red complex, which includes Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia (formerly Bacteroides forsythus), are recognized as the most important pathogens in adult periodontal disease.

Who discovered Treponema Denticola?

Treponema denticola. Around 400 years ago a man named Antonie van Leeuwenhoek took some scrapings from his mouth and looked at them under a rudimentary microscope. Imagine to your surprise that you found little corkscrew shaped cells, a form that no one had ever thought a living cell could come in.

What are clinical signs of periodontitis?

Signs and symptoms of periodontitis can include:

• Swollen or puffy gums.
• Bright red, dusky red or purplish gums.
• Gums that feel tender when touched.
• Gums that bleed easily.
• Pink-tinged toothbrush after brushing.
• Spitting out blood when brushing or flossing your teeth.
• Bad breath.
• Pus between your teeth and gums.

What kind of disease is Treponema denticola associated with?

Treponema denticola is a spirochete bacterium associated with progression of periodontal diseases, infectious diseases that destroy attachment of teeth.

What can I do to get rid of Treponema denticola?

Medicated mouthwash can help treat periodontal disease. Regular cleaning, including both the teeth and subgingival area, can remove buildups of plaque and biofilm to dislodge Treponema denticola. Patients with severe oral disease may need more extensive cleaning and scaling to successfully restore the surface of the teeth.

When to use a reactive treponemal test for syphilis?

A reactive treponemal test most likely indicates infection by T pallidumbut is not sufficient to determine disease activity and make treatment decisions (table 1). A reactive test can be seen in patients with a history of syphilis who has been treated.