What is the formula for GFR?

Your GFR tells you how much kidney function you have. It is defined as the sum of the filtration rates of all your functioning nephrons (filtering units making up the kidneys). An estimate of the normal value for your GFR can be obtained by using the equation: GFR = 140 – [your age].

What is a normal GFR in Children?

On the basis of these small studies, GFR would be expected to range between approximately 85 and 150 ml/min per 1.73 m2 in 95% of healthy adolescents, with approximately 16% having GFRs <100 ml/min per 1.73 m2 (1 SD below the mean).

How is pediatric creatinine clearance calculated?

Height is measured in cm. Serum creatinine is measured in mg/dL. Measured creatinine should be in steady state. This formula tends to overestimate the actual creatinine clearance and should be used with caution….Creatinine Clearance: Original Schwartz Estimate.

Which eGFR equation is best?

Glomerular filtration rate (GFR) is the best overall index of kidney function. Normal GFR varies according to age, sex, and body size, and declines with age. The National Kidney Foundation recommends using the CKD-EPI Creatinine Equation (2021) to estimate GFR.

What is race in eGFR calculation?

Race was originally included in eGFR calculations because clinical trials demonstrated that people who self-identify as Black/African American can have, on average, higher levels of creatinine in their blood.

What is eGFR value?

eGFR (estimated glomerular filtration rate) is a measure of how well your kidneys are working. Your eGFR is an estimated number based on a blood test and your age, sex, body type and race. eGFR is considered a mostly reliable test for doctors to know how well your kidneys are working.

What is a normal GFR for a 12 year old?

Premature 0.3 – 1.0 mg/dL Neonates 0.2 – 0.9 mg/dL 2-12 months 0.2 – 0.4 mg/dL 1-2 years 0.2 – 0.5 mg/dL 3-4 years 0.3 – 0.7 mg/dL 5-6 years 0.3 – 0.7 mg/dL 7-8 years 0.2 – 0.6 mg/dL 9-10 years 0.3 – 0.7 mg/dL 11-12 years 0.3 – 0.9 mg/dL 13-15 years 0.4 – 0.9 mg/dL Males 16-17 years old 0.6 – 1.2 mg/dL Females 16-17 …

What is the normal range for GFR?

A GFR of 60 or higher is in the normal range. A GFR below 60 may mean kidney disease. A GFR of 15 or lower may mean kidney failure.

How do you calculate GFR from creatinine?

About eGFR eGFR is estimated GFR calculated by the abbreviated MDRD equation : 186 x (Creatinine/88.4)-1.154 x (Age)-0.203 x (0.742 if female) x (1.210 if black).

What is the best GFR?

If GFR goes down, it’s a bad sign. If creatinine goes up, it’s a bad sign. In general, a “good” GFR number is above 60 and a “good” creatinine number is below 1.2.

When to use a pediatric GFR calculator?

Instructions The pediatric GFR calculator is for use in children under 19 years old. If values for cystatin C and/or BUN are not entered, the calculator will generate GFR estimates using the creatinine-based “Bedside Schwartz” equation only (currently considered the best method for estimating GFR in children).

How to estimate the glomerular filtration rate in infants?

A simple estimate of glomerular filtration rate in full-term infants during the first year of life. J Pediatr. 1984 Jun;104 (6):849-54. Schwartz GJ, Gauthier B.

How to calculate GFR for glomerular filtration rate?

GFR = 141 × min (Scr /κ, 1)α × max (Scr /κ, 1)-1.209 × 0.993Age × 1.018 [if female] × 1.159 [if black] where: Scr is serum creatinine in mg/dL, κ is 0.7 for females and 0.9 for males, α is -0.329 for females and -0.411 for males, min indicates the minimum of Scr /κ or 1, and. max indicates the maximum of Scr /κ or 1.

Can a GFR equation be used for acute renal failure?

The Modification of Diet in Renal Disease Study (MDRD) equation cannot be used for acute renal failure. It is only useful in estimating glomerular filtration rate (GFR) in stable chronic kidney disease.