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What is proximal gastric vagotomy?

What is proximal gastric vagotomy?

Proximal gastric vagotomy (PGV) selectively denervates the acid-producing part of the stomach (the body and fundus). The operation preserves the vagal innervation of the antrum and pylorus, making a gastric drainage procedure unnecessary.

What is gastric vagotomy?

A vagotomy is a type of surgery that removes all or part of your vagus nerve. This nerve runs from the bottom of your brain, through your neck, and along your esophagus, stomach, and intestines in your gastrointestinal (GI) tract.

What is the effect of vagotomy on gastric secretion?

Vagotomy markedly reduced interdigestive gastric secretion, determined as night secretion, in ulcer patients. The vagotomy was originally performed as a truncal vagotomy without a drainage operation; this resulted in a high frequency of postoperative gastric retention and in 5 to 10% in secondary gastric ulcers.

What are the side effects of a vagotomy?

Vagotomy Side Effects

  • Diarrhea.
  • Cholestasis, or the stopping or slowing of bile in the gallbladder.
  • Gallstones.
  • Delayed gastric emptying.
  • Dumping syndrome.
  • Weight loss.
  • Bleeding.
  • Injury to the stomach, esophagus, and/or major blood vessels during surgery.

When do you do vagotomy?

Vagotomy is indicated for patients who develop acute complications from peptic ulcer disease (ie, bleeding, perforation, obstruction) or chronic intractable symptoms such as pain, despite being on maximally tolerated medical therapies.

How successful is pyloroplasty surgery?

Conclusion: Laparoscopic pyloroplasty improves or normalizes gastric emptying in nearly 90% of gastroparesis patients with very low morbidity. It significantly improves symptoms of nausea, vomiting, bloating, and abdominal pain.

How does vagotomy decrease the gastric acid secretion?

The rationale for vagotomy is the elimination of direct cholinergic stimulation of gastric acid secretion. The released acetylcholine stimulates acid secretion via a specific receptor on the parietal cell. Vagotomy also renders the acid-producing parietal cells less responsive to histamine and gastrin.

Does vagotomy affect gastrin?

It is concluded that increased secretion of gastrin after vagotomy secures trophic and compensatory-adaptation processes.

How effective is a vagotomy?

Of 564 patients undergoing surgery, usually a vagotomy and gastroenterostomy, 515 (91.3%) were followed for at least 10 years. There was a good to excellent result in 86% of the patients. The recurrence rate was 7.6% with a follow-up of over 10 years.