# What if MCH and MCHC are high?

## What if MCH and MCHC are high?

High MCH value can often be caused by anemia due to a deficiency of B vitamins, particularly B-12 and folate. Both of these vitamins are required by your body in order to make red blood cells. These types of anemia can develop if your diet is low in B vitamins or if your body does not absorb B-12 or folate properly.

How do you calculate MCHC from MCH?

RBC is per million cells. MCV = Hct × 10/RBC (84-96 fL) •Mean corpuscular Hb (MCH) = Hb × 10/RBC (26-36 pg) •Mean corpuscular Hb concentration (MCHC) = Hb × 10/Hct (32-36%) A rapid method of determining whether cellular indices are normocytic and normochromic is to multiply the RBC and Hb by 3.

How do you calculate MCH?

MCH is obtained by dividing the amount of hemoglobin in a blood sample by the amount of red blood cells and then multiplying the result by 10. The preferred measurement unit is the picogram (pg), which is equivalent to 10-12 grams.

### How do you lower MCHC levels?

The best way to prevent a low MCHC level is to prevent iron deficiency anemia. To do this, try to make sure you’re getting enough iron and vitamin B6 in your diet. Keep in mind that the iron in spinach is not as readily absorbed because of its oxalic acid content.

Why is MCHC increased in hereditary spherocytosis?

In spherocytosis, the MCHC is increased due to loss of membrane and the consequent spherical shape assumed by the cell. The general availability of RDW as a measure of anisocytosis helps further in the evaluation of anemias based on morphology (see Table 152.2).

Why is MCHC high in hereditary spherocytosis?

## How is MCHC calculated?

MCHC is calculated by multiplying the hemoglobin result from the CBC panel by 100 and then dividing by the hematocrit result. The reference range for MCHC in adults is 33.4–35.5 grams per deciliter (g/dL). If your MCHC value is below 33.4 grams per deciliter, you have low MCHC.

Is MCH same as MCHC?

MCH quantifies the amount of hemoglobin per red blood cell. The normal values for MCH are 29 ± 2 picograms (pg) per cell. MCHC indicates the amount of hemoglobin per unit volume. In contrast to MCH, MCHC correlates the hemoglobin content with the volume of the cell.