How does anthelmintic resistance develop?

How does anthelmintic resistance develop?

Development of anthelmintic resistance Under these circumstances resistance arises as a result of selection through exposure of the worm population to an anthelmintic. When an animal is optimally exposed to an anthelmintic the only worms that should survive are those that carry the genes that confer resistance.

Can parasites develop resistance?

Science shows that antiparasitic resistance can’t be stopped. Parasites will continue to evolve and develop resistance; however, this natural process may be slowed down.

What drug kills helminths?

Anthelmintics are a type of medicine that kills helminths. Helminths are worm-like parasites such as flukes, roundworms, and tapeworms. It is important that anthelmintics are selectively toxic to the parasite and not the host.

What does praziquantel treat?

Praziquantel is used to treat schistosoma (infection with a type of worm that lives in the bloodstream) and liver fluke (infection with a type of worm that lives in or near the liver). Praziquantel is in a class of medications called anthelmintics. It works by killing the worms.

How can anthelmintic resistance be overcome?

Targeted selective treatments attract the interest of scientists towards this direction. Additionally, adoption of strict quarantine measures and a combination drug strategy are two important methods of preventing of anthelmintic resistance.

What does anthelmintic resistance mean?

Anthelmintic resistance (AR) is defined by Køhler as genetically transmitted loss of sensitivity of a drug in worm populations that were previously sensitive to the same drug [6]. In a worm population, alleles coding for resistance will be present as a result of mutations, also in unexposed populations.

What are anti amoebic drugs?

Antiamoebic drugs vary in efficacy at the three sites where parasites commonly exist and generally are divided into two classes based on their main site of activity. Luminal amoebicides act principally in the bowel lumen, and tissue amoebicides act principally in the bowel wall and in the liver.