What is Peripapillary retinoschisis?

Peripapillary retinoschisis is a splitting of the intraretinal layers adjacent to the optic nerve head and can be observed in degenerative myopia, tilted-disc syndrome, morning glory syndrome, optic nerve colobomas, and optic nerve pits.

What is degenerative retinoschisis?

Degenerative retinoschisis is an acquired idiopathic condition characterized by gradual peripheral splitting of the retinal layers, typically between inner nuclear and outer plexiform layer.

What causes degenerative retinoschisis?

X-linked retinoschisis is caused by a problem in the X chromosome, making it a genetic condition. It almost always occurs in young males because they only have one X chromosome. Whereas females have two X chromosomes — so if there’s a problem with one of them, the other one usually counteracts it.

How common is degenerative retinoschisis?

Degenerative retinoschisis This type of retinoschisis is very common with a prevalence of up to 7 percent in normal persons. Its cause is unknown. It can easily be confused with retinal detachment by the non-expert observer and in difficult cases even the expert may have difficulty differentiating the two.

Is Retinoschisis curable?

There is no medical treatment for degenerative retinoschisis; however, vitrectomy surgery is occasionally required for complications related to either type of retinoschisis.

Is retinoschisis curable?

Does retinoschisis cause floaters?

Patients with retinoschisis should be educated about the signs and symptoms of retinal detachment. Patients need to understand that delaying the reporting of the sudden appearance of flashes of light, floaters, sparkles of light, or shadows, can seriously increase the risk of permanent vision decrease or loss.

How is the circular extent of peripapillary retinoschisis determined?

Peripapillary retinoschisis was defined when the splitting of the inner or outer retinal layers adjoined the optic disc margin in the cpRNFL SD-OCT B-scans. The circular extent of the retinoschisis was determined based on IR and cpRNFL B-scan images.

Are there any cases of retinoschisis in glaucomatous eyes?

The present study investigated 22 cases of peripapillary retinoschisis in glaucomatous eyes. The retinoschisis was attached to the optic nerve and topographically correlated with RNFL defect. It often resolved spontaneously without causing severe visual disturbance.

How is intraocular pressure related to retinoschisis?

Multivariate analysis showed a significant influence of a higher intraocular pressure at SD-OCT scanning on the presence of retinoschisis (Odds ratio  = 1.418, P = 0.001). The present study investigated 22 cases of peripapillary retinoschisis in glaucomatous eyes.

Which is part of the optic disc is affected by retinoschisis?

In the 22 glaucomatous eyes with retinoschisis, the schisis was attached to the optic disc and overlapped with the retinal nerve fiber layer (RNFL) defect. The RNFL was the layer most commonly affected by the retinoschisis, either alone or together with other deeper layers.