What is the life expectancy of HER2-positive metastatic breast cancer?

Results: From 2004 to 2014, 422 HER2-positive MBC patients received first-line trastuzumab. With a median follow-up of 48 months, median OS and PFS were 63 months (CI95%, 50-71), and 18 months (CI95%, 15-21) respectively.

Can metastatic HER2-positive breast cancer be cured?

Metastatic (stage 4) HER2-positive breast cancer is not curable—but it is treatable, and options continue to expand and improve.

Can HER2-positive breast cancer come back?

HER2-positive breast cancer is more aggressive and more likely to recur, or return, than HER2-negative breast cancer. Recurrence can happen anytime, but it usually takes place within 5 years of treatment. The good news is that recurrence is less likely today than ever before.

Is triple positive breast cancer likely to recur?

During the study period, recurrences were reported in 11 of 169 patients (6.5%) with triple-positive breast cancer, 29 of 724 patients (4.0%) with the luminal A subtype, and 22 of 206 patients (10.7%) with the HER2-enriched subtype.

What is the longest anyone has lived with metastatic breast cancer?

Stage 4: Kim Green Has Lived With Metastatic Breast Cancer For Past 19 Years. Kim Green defies the odds for those living with incurable metastatic breast cancer. Her mother died of metastatic breast cancer at 37, but Green has been living with it for 19 years.

Can I live 10 years with metastatic breast cancer?

While there is no cure for metastatic breast cancer, there are treatments that slow the cancer, extending the patient’s life while also improving the quality of life, Henry says. Many patients now live 10 years or more after a metastatic diagnosis.

Is HER2-positive breast cancer more aggressive?

In about 1 of every 5 breast cancers, the cancer cells have extra copies of the gene that makes the HER2 protein. HER2 -positive breast cancers tend to be more aggressive than other types of breast cancer.

How long is chemo for HER2-positive?

Cycles can last anywhere from about two to four weeks, depending on the combination of drugs. Chemotherapy generally lasts about three to six months. The total length of chemotherapy treatment may vary depending on the stage of breast cancer and a number of other factors.

What is the survival rate for triple positive breast cancer?

The relative 5-year survival rate for stage 3 breast cancer is 86 percent, according to the American Cancer Society . This means that out of 100 people with stage 3 breast cancer, 86 will survive for 5 years.

What is the survival rate for HER2 positive breast cancer?

The survival rate for HER2 positive breast cancer is a very broad, general indication of outcomes only. Those who are learning about the survival rate for HER2 positive breast cancer should remember that it does not predict what will happen for any particular patient.

Which is more aggressive HER2 positive or HER2 negative?

An overexpression of HER2 protein causes out-of-control reproduction of breast cells. HER2-positive breast cancers tend to be more aggressive than HER2-negative breast cancers. Along with tumor grade and cancer stage, HR and HER2 status help determine your treatment options.

Can a HER2 positive breast cancer be treated with leptin?

Leptin can impair response to Herceptin in breast cancer cells. However, recent evidence suggests that treating with Herceptin concurrently with chemotherapy may potentially equalize disease free survival rates between obese and normal weight women with HER2+ breast cancer.

What are the survival rates for triple negative breast cancer?

Breast cancers that are triple negative have the lowest survival rates. The 4-year survival rates are as follows: HR+/HER2-: 92.5%. HR+/HER2+: 90.3%. HR-/HER2+: 82.7%. HR-/HER2-: 77.0%. HER2+ Status, Cancer Stage, and Survival. The importance of HER2 status for survival will depend on how far the cancer has spread.